The state of the environment and the economy require altering the way we approach business transactions (cf. the UN Sustainable Development Goals). Innovative sustainable interventions addressing social inequality and environmental degradation are required to create employment opportunities for sustainable growth. The aim of the Co-LIFE project is to produce innovative educational measures in impact-focused entrepreneurship (IFE) in four (4) Indian HEIs. Project partner institutions in Europe and India have come together to co-develop educational content (course curriculum), learning materials, and novel innovative pedagogics to advance IFE-based education in India. This educational collaboration between Indian and EU-based HEIs (including students as co-developers) involves creating a tight stakeholder ecosystem in India and between India and the EU. The proposal involves local companies, non-academic organisations and other relevant stakeholders bringing innovative added value for social inclusion. This will produce positive social, economic and environmental results through knowledge-sharing. Through close collaboration between HEIs, companies and associations, e. g. via impact-focused entrepreneurship activities the Co-LIFE project will create change in communities, in the short and long term. India needs sustainable interventions to address and exploit their demographics and their entrepreneurial growth and vibrant ecosystem. The goal is Erasmus+ CBHE goals. Additionally, enhancing intercultural relations between the EU and India among HEIs, students, teaching staff, and local businesses and associations is an objective. HEIs and the ecosystem created in the project will benefit from exchanging best practices in learning and teaching methods and practical ideas towards employment and sustainable development in their respective areas.