We are HEROES (Higher Education for Resilience-Oriented and Empowered Societies), a European University Alliance of 9 young, agile and regionally embedded professional higher education institutions from Belgium, Czech Republic, Denmark, Finland, Germany, Lithuania, the Netherlands, Portugal, and Sweden. United, we reach 120,000 students, from the associate degree to the PhD level, covering all disciplines and sectors with a distinct applied sciences perspective. Our collaboration focuses on smart regional resilience, defined as the capacity of local communities, businesses and natural environments to anticipate, adapt, and recover from disruptions by strategically applying smart technologies. HEROES focuses on human-centred, nature-positive and resilience enhancing digital innovation. The HEROES Alliance will establish a green and inclusive inter-university campus, driven by a long-term joint educational strategy and seamless mobility. Our campus is organised in three flagship areas: 'EDUCATION4HEROES' (joint offerings at bachelor, master, and doctoral levels), 'HEROES4REGIONS' (challenge-based education, research, and innovation programmes), and 'HEROES4EVER' (lifelong learning opportunities for professionals and staff). These are supported by four cornerstones: shared resources for governance, stakeholder engagement, mobility support, and innovative virtual collaboration. Aiming to enhance employability of people and resilience of regions, HEROES will have an impact on over 60,000 students and 7,000 staff directly, as well as on other higher education institutions, organisations and citizens. Through partnerships, the Alliance’s impact extends beyond the HEROES regions to the EU neighbourhood and the Global South. By transforming the talents of Europeans into superpowers, HEROES strengthens a unified, innovative, digitally advanced, interconnected and, sustainable Europe that holds European values in high regard, and is open and connected to the wider world.